Working with samples with high cell viability and free of debris is a key prerequisite to obtain accurate and reliable results in single-cell sequencing. This is particularly important for gene expression analysis since only viable nucleated cells will generate functional libraries. Our strainers and removal reagents help you to clean up your single-cell suspensions from unwanted material such as, cell aggregates, dead cells, debris or erythrocytes to get the best possible genomic analysis results.
Application of different clean up steps on mouse tumor cell suspensions helps to remarkably increase the quality of single-cell genomic data.
MACS SmartStrainers allow the removal or large particles and cell aggregates in cell suspensions from solid tissues or blood samples. Their special design enables a fast filtration without clogging and easily fit into 15 mL and 50 mL tubes.
Removing large particles and cell aggregates in cell suspensions from solid tissues or blood samples provides purer samples that will produce higher quality data.
Use the Dead Cell Removal Kit for the fast and straight forward magnetic depletion of dead cells from blood samples, cryopreserved cells, or cell suspensions from fresh solid tissues containing robust cells, such as fibroblasts, epithelial cells, tumor cells, or immune cells. When combined with the autoMACS® Pro Separator, the process of dead cell removal can be performed in an automated way by just clicking a button.
The Debris Removal Solution is a ready-to-use density gradient reagent that allows the fast and convenient removal of subcellular debris in cell suspensions containing fragile cells, such as adult neurons, adult cardiomyocytes or hepatocytes , and kidney. In addition, lysis of red blood cells with the Red Blood Cell Lysis Solution helps to increase the yields of viable nucleated cells.