Maintaining and expanding your umbilical cord derived mesenchymal stem cells (MSCs) is of first priority for standardized and differentiation potential. No matter your experimental needs, our solutions include complete workflow service from tissue dissection to MSC isolation, expansion, differentiation and immunomodulation assays. With specialized dissociation kits involving automated dissociation of umbilical cord tissue, the potential for MSC expansion in our xeno- and serum-free medium provide the structural foundation and continued support you need for viable downstream applications.
Human umbilical cord tissue can be dissociated into a single-cell suspension by combining mechanical dissociation with enzymatic degradation of the extracellular adhesion proteins that maintain the tissue's structural integrity. Our Umbilical Cord Dissociation Kit, human and the gentleMACS Dissociators are the perfect combination for standardized and reliable dissociation of umbilical cord tissue.
Get your research off to the right start. Rely on excellent sample preparation with the gentleMACS Dissociator family. Start your experiments off smart with standardized and reproducible tissue dissociation.
Our cell culture options provide reliable solutions for the maintenance and expansion of MSCs with preserved differentiation potential and immunomodulation ability.
The MSC Phenotyping Kit was developed for the standardized identification and phenotyping of cultured human MSCs by flow cytometry based on the defined ISCT standards.
We provide a variety of media options that support the differentiation of MSCs into adipocytes, osteoblasts, and chondrocytes. The different StemMACS Differentiation Media are suitable for the analysis or quality control of the differentiation capacity of expanded MSCs, as well as in vitro studies focusing on the processes involved in MSC differentiation, including gene expression and protein profiling.
The suppression potential of MSCs varies among in vitro expanded cells and shows donor-dependent differences. MSCs can be “licensed” by inflammatory cytokines such IFN-γ and TNF-α to become more immunosuppressive and show a more homogeneous phenotype in this regard. The MSC Suppression Inspector, human was developed for standardized characterization of the immunomodulatory function of MSCs by co-culture with CD4+CD25– or CD4+ responder T (Tresp) cells.