Specifications for IL-10 Antibody, anti-mouse, REAfinity™
Overview
Clone REA1008 recognizes the interleukin-10 (IL-10) cytokine, which is predominantly secreted by CD4
+ T cells and antigen-presenting cells, such as monocytes/macrophages and dendritic cells. IL-10 has important suppressive functions on immune responses and is believed to be involved in the maintenance of tolerance. IL-10 blocks activation of cytokine synthesis by Tʜ1 cells, activated monocytes, and NK cells. It can stimulate immunoglobulin production by B cells.
Additional information: Clone REA1008 displays negligible binding to Fc receptors.
Alternative names
IL10, CSIF, Interleukin-10Detailed product information
Technical specifications
| Clone | REA1008 |
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| Clonality | monoclonal |
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| Isotype | recombinant human IgG1 |
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| Isotype control | REA Control Antibody, human IgG1 |
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| Host | human cell line |
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| Type of antibody | Primary antibodies, Recombinant antibodies |
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| Species | mouse |
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| Antigen | IL-10 |
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| Alternative names of antigen | IL10, CSIF, Interleukin-10 |
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| Molecular mass of antigen [kDa] | 19 |
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| Distribution of antigen | dendritic cells, macrophages, monocytes, antigen-presenting cells, CD4+ T cells |
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| Entrez Gene ID | 16153 |
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| RRID | AB_2727718, AB_2727791, AB_2727719, AB_2727792, AB_2727720, AB_2727793, AB_2727721, AB_2727790 |
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