Type of antibody:
Primary antibodies, Recombinant antibodies
recombinant human IgG1
Alternative names:
c-kit, PBT, SCFR, KIT

Specifications for CD117 Antibody, anti-human, REAfinity™


Clone REA787 recognizes the human CD117 antigen, also known as c-kit or SCF receptor, which is a 145 kDa receptor tyrosine kinase that is involved in stem cell signaling, activation, and proliferation. The CD117 antigen is expressed on about 1–3% of mononuclear cells from peripheral blood mononuclear cells (PBMCs) or cord blood and on up to 10% of bone marrow cells. CD117 is further expressed on basophils, myeloid dendritic cells, TCRα/β
T cells, CD19
B cells, and CD56
NK cells, as well as on mast cells, melanocytes, and acute myeloid leukemia (AML) blasts. Clone REA787 recognizes a different epitope than clone AC126 and may interfere with SCF-binding. It is therefore not recommended for indirect cell isolation, but is optimal for flow cytometric analysis of cells separated with the CD117 MicroBead Kit, human.
Additional information: Clone REA787 displays negligible binding to Fc receptors.

Alternative names

c-kit, PBT, SCFR, KIT

Detailed product information

Technical specifications

Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (S), human IgG1
Hosthuman cell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Alternative names of antigenc-kit, PBT, SCFR, KIT
Molecular mass of antigen [kDa]107
Distribution of antigenB cells, macrophages, fibroblasts, mast cells, megakaryocytes, myeloid leukemia cells, T cells, red blood cells, NK cells, cancer stem cells, hematopoietic stem and progenitor cells, leukemia cells, bone marrow, brain, kidney, liver, lung
Entrez Gene ID3815
RRIDAB_2654577, AB_2654578, AB_2654579, AB_2654580, AB_2654581, AB_2654582, AB_2654583, AB_2654584, AB_2654585, AB_2654586, AB_2654587, AB_2654588, AB_2654589, AB_2904682, AB_2904681, AB_2654576

Resources for CD117 Antibody, anti-human, REAfinity™


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References for CD117 Antibody, anti-human, REAfinity™


  1. Bühring, H. J. et al. (1991) The product of the proto-oncogene c-kit (P145c-kit) is a human bone marrow surface antigen of hematopoietic precursor cells which is expressed on a subset of acute non-lymphoblastic cells. Leukemia 5: 854-860
  2. Kubo, H. et al. (2008) Increased cardiac myocyte progenitors in failing human hearts. Circulation 118: 649-657
  3. Berglund, E. et al. (2013)
    Evidence for Ca
    -regulated ATP release in gastrointestinal stromal tumors.
    Exp. Cell Res. 319(8): 1229-1238

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