Clone:
REA1312
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
MICS, IHC, IF
Alternative names:
PECAM1, CD31/EndoCAM, EndoCAM, GPIIA', PECA1, PECAM-1

Specifications for CD31 Antibody, anti-human, REAfinity™

Overview

Clone REA1312 recognizes the human CD31 antigen, a 120–140 kDa single-chain transmembrane glycoprotein, which is also known as EndoCAM or PECAM1. CD31 is highly expressed on endothelial cells, especially at their juncture. It is also present on virtually all monocytes, platelets, granulocytes and lymphocyte subsets. During maturation of CD4
+
T cells, the expression of CD31 changes: CD4
+
recent thymic emigrants (RTEs) express CD31 in contrast to central naive T cells.
In histological tissue sections CD31 is mainly used for endothelial cells, futher more it is a marker for angiomas and angiosarcomas. CD31 plays a role in leukocyte migration, angiogenesis, and integrin activation. Additional information: Clone REA1312 displays negligible binding to Fc receptors.

Alternative names

PECAM1, CD31/EndoCAM, EndoCAM, GPIIA', PECA1, PECAM-1

Detailed product information

Technical specifications

CloneREA1312
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (I), human IgG1
Hosthuman cell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman
AntigenCD31
Alternative names of antigenPECAM1, CD31/EndoCAM, EndoCAM, GPIIA', PECA1, PECAM-1
Distribution of antigenendothelial cells, monocytes, platelets, granulocytes, lymphocytes, kidney, bone marrow, spleen, smooth muscle, colon
RRIDAB_2904938

Resources for CD31 Antibody, anti-human, REAfinity™

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

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