Human pluripotent stem cells (PSCs), including induced pluripotent stem cells (iPS cells) and embryonic stem cells (ES cells), can self-renew infinitely and give rise to cells of all three germ layers, thus holding great promise in regenerative therapies. However, with varying cell type needs and technical challenges influencing cell manufacturing, the ability to leverage automation, process integrity, quality, and scalability becomes vital for success. The CliniMACS Prodigy® Adherent Cell Culture process, together with the GMP compliant CliniMACS Prodigy Tubing Set 730, meets the demands for automated, closed, and scalable manufacturing of PSCs and their derivatives for clinical applications.
View how the CliniMACS Prodigy Adherent Cell Culture process automates adherent stem cell expansion and differentiation in a scalable and closed system saving you time while realizing reliable and consistent cell products.
The CliniMACS Prodigy Adherent Cell Culture process offers nine modules representing different workflow steps in the cell manufacturing process. The modular nature allows users to build customized and automated manufacturing processes.
The CliniMACS Prodigy Tubing Set 730 is a GMP-compliant, single-use, and biocompatible tubing set that provides a functionally closed system for cell manufacturing. Consisting of tubing, bags, and sterile access ports, the tubing set provides a sterile fluid path to facilitate all required cell processing steps without contamination. Additionally, external culture vessels can be connected to the CliniMACS Prodigy Tubing Set 730, enabling scalable cell manufacturing processes.
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