Optimized tissue sample storage for genomic analysis
Tissue sample storage is necessary when you need to collect and store samples until ready for further processing or shipping to collaboration sites. Especially for genomic analyses, ensuring the right conditions for tissue sample storage are key to avoid changes in cellular composition and minimize cellular stress responses that could negatively impact downstream analyses. The MACS Tissue Storage Solution ensures to uphold tissue quality and integrity to get reliable genomic results in next generation sequencing and single-cell sequencing.
Prevention of cellular stress responses after short-term storage of mouse tumors
After 48 hours of storage in MACS Tissue Storage Solution, mouse tumors showed minimal changes in cellular stress-related gene expression as compared to fresh tumors. This is an advantage to increasing work-time flexibility in a genomics lab and for reliable downstream gene expression analyses.
Tissue sample storage in MACS Tissue Storage Solution enables flexibility in sample processing by allowing the optimal storage of solid tissues for at most 48 h at 2–8°C. It has been validated with a variety of human and murine tissues including tumor, lung, spleen, brain, or skeletal muscle.
Optimal storage of murine tumors up to 48 h
Freshly extracted tumor tissue has been validated for storage up to 48 h in MACS Tissue Storage Solution without compromising cell viability or immune cell composition.
Preservation of TIL composition and activation status
Flow cytometric analysis of TIL populations after storage in MACS Tissue Storage Solution show preservation of TIL phenotype and composition. Uncompromised immune cell composition allows for reliable results in further analyses.
