Clone:
REA321
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC, MICS, IF, IHC, MC
Alternative names:
FUT4, CD15, ELFT, FCT3A, FUC-TIV, FUTIV, Lex

Specifications for SSEA-1 Antibody, anti-human/mouse, REAfinity™

Overview

Clone REA321 recognizes the human and mouse stage specific embryonic antigen 1 (SSEA-1) antigen, which is a Lewis blood group related carbohydrate antigen, also known as CD15. SSEA-1 is expressed on human myelomonocytic cells and is present on neutrophils, eosinophils, and some monocytes, but not on basophils or lymphocytes. The antigen is also expressed on Hodgkin/Reed-Sternberg cells. SSEA-1 is a common surface marker for pluripotency on mouse ES and iPS cells. On human cells in contrast, SSEA-1 is expressed only on early differentiating cells.
Additional information: Clone REA321 displays negligible binding to Fc receptors.

Alternative names

FUT4, CD15, ELFT, FCT3A, FUC-TIV, FUTIV, Lex

Detailed product information

Technical specifications

CloneREA321
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (S), human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman, mouse
AntigenSSEA-1
Alternative names of antigenFUT4, CD15, ELFT, FCT3A, FUC-TIV, FUTIV, Lex
Distribution of antigenmonocytes, stem cells, eosinophils, neutrophils, ES and iPS cells
RRIDAB_2728020, AB_2728043

Resources for SSEA-1 Antibody, anti-human/mouse, REAfinity™

Certificates

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References for SSEA-1 Antibody, anti-human/mouse, REAfinity™

Publications

  1. Son, M. J. et al. (2009) SSEA-1 is an enrichment marker for tumor-initiating cells in human glioblastoma. Cell Stem Cell 4(5): 440-452
  2. Knowles, B. B. et al. (1982) Murine embryonic antigen (SSEA-1) is expressed on human cells and structurally related human blood group antigen I is expressed on mouse embryo. Dev. Biol. 93(1): 54-58
  3. Nudelman, E. et al. (1980) Monoclonal antibody directed to the stage-specific embryonic antigen (SSEA-1) reacts with branched glycosphingolipid similar in structure to Ii antigen. Biochem. Biophys. Res. Commun. 97(2): 443-451

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