Owl biomedical, Inc.

Established in 2011, Owl biomedical produces exclusive cell sorting micro-electro mechanical systems (MEMS) technology for application in cell therapy, cancer diagnostics, and basic research. In February 2013, Owl biomedical joined the Miltenyi Group.

Facts & figures


Microchip-based cell sorting technology


Santa Barbara, CA, USA

Employee number

> 25 

General information

Owl biomedical houses part of the research, development, and manufacturing for the MACSQuant® Tyto® Cell Sorter and associated microchips. This team brings together expertise in flow sorting and microchip engineering to make the next generation in cell sorting a reality.

MACSQuant® Tyto® Cartridge

Expertise and Technology

Bringing together the best talent across various disciplines, Owl biomedical boasts expertise in microfluidic, optical, and mechanical design, system software as well as biological application. We use state-of-the-art microfabrication techniques to produce the cell-sorting chip at the heart of the MACSQuant Tyto Cell Sorter. It combines mechanically-enabled microchips and a swift micro-valve to perform fluorescence-activated cell sorting, for use in all areas – from basic research to cell therapeutic applications.


  • 2009 – First Nanosorter® (precursor to MACSQuant Tyto Cell Sorter) sorts cells via microchip & fluorescent labeling
  • 2011 – Founding of Owl biomedical 
  • 2011 – First Nanosorter installed at Fred Hutch Cancer Research Center 
  • 2013 – Owl biomedical acquired by Miltenyi Biotec
  • 2014 – First clinical trial started at MDAnderson with the Nanosorter for Ag+ T cell therapy for melanoma
  • 2015 – First patient infused with micro-fluidically sorted cells from the Nanosorter
  • 2016 – MACSQuant Tyto Cell Sorter approved for clinical trials at MDAnderson for Ag+ T cell therapy for melanoma
  • 2016 – First patient infused cells sorted with MACSQuant Tyto Cell Sorter
  • 2019 – First clinical trial performed in Japan with MACSQuant Tyto Cell Sorter for Parkinson’s treatment
  • 2019 – First MACSQuant Tyto Cell Sorter installed in a BSL3 at the NIH
  • 2021 – The 200th MACSQuant Tyto Cell Sorter shipped
  • 2022 – Manufacture of the 1,000,000th microchip

Open positions

See open positions at Owl biomedical Inc.

Owl biomedical Inc. 
75 Robin Hill Rd., Santa Barbara, CA 93117, USA
Phone +1 866-811-4466

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