Clone:
6B11
Type of antibody:
Primary antibodies, Functional-grade antibodies
Isotype:
mouse IgG1κ, mouse IgG1
Applications:
FC, FA

Specifications for iNKT Antibody, anti-human

Overview

NKT cells represent a distinct lymphocyte population that co-expresses T cell and NK cell surface markers. A subset of human NKT cells, referred to as iNKT cells, expresses an invariant TCR α-chain with certain TCR β-chains (Vα24-Jα18 combined with Vβ11). The iNKT cells are implicated in immunoregulatory processes such as tolerance, host defense, and tumor surveillance.

Detailed product information

Technical specifications

Clone6B11
Clonalitymonoclonal
Isotypemouse IgG1κ, mouse IgG1
Isotype controlIsotype Control Antibody, mouse IgG1
Hostmouse
Type of antibodyPrimary antibodies, Functional-grade antibodies
Specieshuman, non-human primate
Cross-reactivity
rhesus monkey (
Macaca mulatta
)
,
cynomolgus monkey (
Macaca fascicularis
)
AntigeniNKT
Distribution of antigenstem cells, NKT cells
Entrez Gene ID28659, 28747, 28582, 28581
RRIDAB_2857736, AB_10829021, AB_2659825, AB_10828344, AB_2659826, AB_2659827, AB_2659828, AB_10829307, AB_2857742

Resources for iNKT Antibody, anti-human

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

Reviews for iNKT Antibody, anti-human

Very Comparable Antibody to Competitors

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Anti-iNKT-PE-Vio770, human (130-104-110)

My work involves enumerating iNKT cells in human blood and tissue samples. For this I have wanted to try Miltenyi Biotec's antibody and compare it to other company brands to see if quality was good, as Miltenyi Biotec's products are highly price competitive. Also, I have been using their MACS beads for cell isolation for a few years. Results: I have switched over to Miltenyi Biotec.

References for iNKT Antibody, anti-human

Publications

  1. Exley, M. et al. (2008) Selective activation, expansion, and monitoring of human iNKT cells with a monoclonal antibody specific for the TCR α-chain CDR3 loop. Eur. J. Immunol. 38: 1756-1766
  2. Montoya, J. C. et al. (2007) Characterization of human invariant natural killer T subsets in health and disease using a novel invariant natural killer T cell-clonotypic monoclonal antibody, 6B11. Immunology 122: 1-14

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