Type of antibody:
Primary antibodies, Recombinant antibodies
recombinant human IgG1
Alternative names:
Spn, Lsn, Lsn1, gpL115, Ly-48

Specifications for CD43 Antibody, anti-rat, REAfinity™


Clone REA503 recognizes the rat CD43 cell surface antigen, also known as leukosialin or sialophorin, which is a 371 amino acid heavily glycosylated single-pass type 1 transmebrane glycoprotein.
CD43 is expressed by most hematopoietic cells including peripheral T cells, NK cells, granulocytes, monocytes, thymocytes, platelets, plasma cells, activated B cells, and hemotopoietic progenitor cells. Leukosialin is involved in the costimulation of cell activation and survival as well as in cell-cell adhesion and anti-adhesion, and plays a role in inducement the apoptosis of T cells and hematopoietic progenitor cells.
Additional information: Clone REA503 displays negligible binding to Fc receptors.

Alternative names

Spn, Lsn, Lsn1, gpL115, Ly-48

Detailed product information

Technical specifications

Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Alternative names of antigenSpn, Lsn, Lsn1, gpL115, Ly-48
Molecular mass of antigen [kDa]38
Distribution of antigenB cells, granulocytes, monocytes, NK cells, platelets, T cells, stem cells, hematopoietic stem and progenitor cells, plasma cells, thymocytes
Entrez Gene ID24796
RRIDAB_2658081, AB_2658082, AB_2658083, AB_2658084, AB_2658085, AB_2658086, AB_2658087, AB_2658088, AB_2658089, AB_2658090, AB_2658091, AB_2658092, AB_2658093, AB_2658080

Resources for CD43 Antibody, anti-rat, REAfinity™


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References for CD43 Antibody, anti-rat, REAfinity™


  1. van den Berg, T. K. et al. (2001) Cutting Edge: CD43 functions as a T cell counterreceptor for the macrophage adhesion receptor Sialoadhesin (Siglec-1). J. Immunol. 166(6): 3637-3640
  2. Killeen, N. et al. (1987) The sequence of rat leukosialin (W3/13 antigen) reveals a molecule with O-linked glycosylation of one third of its extracellular amino acids. EMBO J. 6(13): 4029-4034
  3. Barclay. A. N. (1981) The localization of populations of lymphocytes defined by monoclonal antibodies in rat lymphoid tissues. Immunology 42(4): 593-600

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