Clone:
REAL232
Type of antibody:
Releasable antibodies, Primary antibodies, Recombinant antibodies
Applications:
FC

Specifications for SSEA-4 Antibody, anti-human,
REAlease
®

Overview

Clone REAL232 is an antibody fragment derived from the full SSEA-4 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAlease Complex to bind markers with high avidity.
Clone REAL232 recognizes the glycolipid carbohydrate epitope stage specific embryonic antigen 4 (SSEA-4). SSEA-4 is found on undifferentiated human embryonic stem (ES) cells, induced pluripotent (iPS) cells, embryonal carcinoma (EC) cells, and embryonic germ (EG) cells as well as a variety of somatic stem cells, such as dental pulp stem cells, umbilical cord blood-derived very small embryonic like stem cells (VSELs), and mesenchymal stromal cells.
The REAlease Kits consist of the respective fluorochrome-conjugated REAlease Complexes and the REAlease Support Kit for removal of the REAlease Complexes and optional relabeling with different fluorochrome-conjugated REAlease Complexes.

Detailed product information

Technical specifications

CloneREAL232
Clonalitymonoclonal
Isotype controlControl Antibody
Hostcell line
Type of antibodyReleasable antibodies, Primary antibodies, Recombinant antibodies
Specieshuman
Cross-reactivityrabbit, mouse, canine, chicken
AntigenSSEA-4
Distribution of antigenES and iPS cells, embryonic germ cells
RRIDAB_2751278, AB_2857555, AB_2751290, AB_2751282, AB_2784462, AB_2784463, AB_2751286

Resources for SSEA-4 Antibody, anti-human,
REAlease
®

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

References for SSEA-4 Antibody, anti-human,
REAlease
®

Publications

  1. Kannagi, R. et al. (1983) Stage-specific embryonic antigens (SSEA-3 and -4) are epitopes of a unique globo-series ganglioside EMBO J. 2(12): 2355-2361
  2. Gang, E. J. et al. (2007) SSEA-4 identifies mesenchymal stem cells from bone marrow. Blood 109(4): 1743-1751
  3. Truong, T. T. et al. (2011) SSEA4 is a potential negative marker for the enrichment of human corneal epithelial stem/progenitor cells. Invest. Ophthalmol. Vis. Sci. 52(9): 6315-6320

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SSEA-4 Antibody, anti-human,
REAlease
®

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