Alternative names:
Mammo­tropin

Specifications for Human Prolactin

Overview

Human prolactin is a recombinant protein optimized for use in cell culture, differentiation studies, and functional assays.

Alternative names

Mammo­tropin

Detailed product information

Background information

Prolactin, also termed luteotropin, is a neuroendocrine hormone. It is produced and secreted by the pituitary gland as well as other tissues such as skin, brain, prostate, uterus, or fat tissue. The hormone is mainly known to stimulate the milk production (lactation) during pregnancy and suckling and can influence the maternal behavior. Besides its role in reproduction and behavior, prolactin seems to exert several metabolic, osmo-, developmental- and immunoregulatory effects. For example, it is involved in pancreatic development, angiogenesis, promotes neurogenesis and can stimulate proliferation of oligodendrocyte precursors. Furthermore, prolactin influences the proliferation and differentiation of lymphocytes, as it can regulate the activities of ornithine decarboxylase and protein kinase C.

Biological activity

  • Proliferation of rat lymphoma Nb2-11 cells
  • research grade: ≥ 1×
    10
    6
    U/mg

Quality description

Research-grade
cytokines are suitable for a wide variety of cell culture applications. They are sterile-filtered prior to lyophilization. Generally, endotoxin levels are <0.1 ng/μg (<1 EU/μg), and purities are >95%. The biological activity is tested in appropriate bioassays.

Resources for Human Prolactin

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

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