Clone:
REA950
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
HLAA

Specifications for HLA-A3 Antibody, anti-human, REAfinity™

Overview

Clone REA950 recognizes the human major histocompatibility complex (MHC) class I molecule HLA-A3, a heterodimer belonging to the HLA-A family and consisting of two subtypes, A3.1 and A3.2. HLA-A has a heavy chain (anchored in the membrane) and a light chain (beta-2 microglobulin). MHC class I molecules are expressed on nearly all nucleated cells and present small intracellular peptides on the cell surface to the immune system. The peptids are recognized by circulating CD8
+
cytotoxic T lymphocytes.
Additional information: Clone REA950 displays negligible binding to Fc receptors.

Alternative names

HLAA

Detailed product information

Technical specifications

CloneREA950
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (S), human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman
AntigenHLA-A3
Alternative names of antigenHLAA
Molecular mass of antigen [kDa]38
Distribution of antigenany cell type
Entrez Gene ID3105
RRIDAB_2727169, AB_2727191, AB_2727170, AB_2727192, AB_2727171, AB_2727261, AB_2727219, AB_2727193, AB_2727172, AB_2727194, AB_2727173, AB_2727190

Resources for HLA-A3 Antibody, anti-human, REAfinity™

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

References for HLA-A3 Antibody, anti-human, REAfinity™

Publications

  1. Jelachich, M. L. et al. (1988) Analysis of the molecular basis of HLA-A3 recognition by cytotoxic T cells using defined mutants of the HLA-A3 molecule. J. Immunol. 141(4): 1108-1113

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