Clone:
REA335
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
ICFC, MICS, IF, IHC
Alternative names:
ALXDRD

Specifications for GFAP Antibody, anti-human/mouse/rat, REAfinity™

Overview

Clone REA335 recognizes the human, mouse, and rat glial fibrillary acidic protein (GFAP), the main intermediate filament protein in mature astrocytes and an important component of the cytoskeleton in astrocytes during development. GFAP is expressed exclusively in astrocytes in the central nervous system. It has been shown to be involved in astrocyte functions, which are important during regeneration, synaptic plasticity, and reactive gliosis. Moreover, different subpopulations of astrocytes have been identified, which are likely to have distinctive tasks in brain physiology and pathology, and which are not only classified by their spatial and temporal appearance, but also by their specific expression of intermediate filaments, including distinct GFAP isoforms.
Additional information: Clone REA335 displays negligible binding to Fc receptors.

Alternative names

ALXDRD

Detailed product information

Technical specifications

CloneREA335
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (I), human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman, mouse, rat
AntigenGFAP
Alternative names of antigenALXDRD
Molecular mass of antigen [kDa]50
Distribution of antigenastrocytes, CNS cells
Entrez Gene ID2670
RRIDAB_2751488, AB_2857665, AB_2857643, AB_2651834, AB_2751525

Resources for GFAP Antibody, anti-human/mouse/rat, REAfinity™

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

References for GFAP Antibody, anti-human/mouse/rat, REAfinity™

Publications

  1. Reeves, S. A. et al. (1989) Molecular cloning and primary structure of human glial fibrillary acidic protein. Proc. Natl. Acad. Sci. U.S.A. 86(13): 5178-5182
  2. Baba H. et al. (1997) GFAP gene expression during development of astrocyte. Dev. Neurosci. 19(1): 49-57
  3. Middeldorp, J. et al. (2011) GFAP in health and disease. Prog. Neurobiol. 93(3): 421-443

Related products for
GFAP Antibody, anti-human/mouse/rat, REAfinity™

3 products available

Seems like you are coming from USA!
Do you want to visit our website in your country?