Clone:
REA759
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
Tnfrsf23, TNFRH1, Dctrailr1, Tnfrsf1al1, mSOB

Specifications for DcTRAIL-R1 (TNFRH1) Antibody, anti-mouse, REAfinity™

Overview

Clone REA759 recognizes the mouse DcTRAIL-R1 antigen, which is a GPI-anchored mouse TNF receptor superfamily member, also known as TNFRH1, tumor necrosis factor receptor superfamily member 23 (Tnfrsf23), or mSOB. DcTRAIL-R1 is expressed on a variety of cells including different tumor cells. Its ligand TRAIL is known to be involved in the inhibition of autoimmune disease. It is reported, that TRAIL suppresses autoimmunity by the inhibition of Tʜ1 cells and the promotion of Tregs.
Additional information: Clone REA759 displays negligible binding to Fc receptors.

Alternative names

Tnfrsf23, TNFRH1, Dctrailr1, Tnfrsf1al1, mSOB

Detailed product information

Technical specifications

CloneREA759
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Speciesmouse
AntigenDcTRAIL-R1 (TNFRH1)
Alternative names of antigenTnfrsf23, TNFRH1, Dctrailr1, Tnfrsf1al1, mSOB
Molecular mass of antigen [kDa]14
Distribution of antigentumor cells
Entrez Gene ID79201
RRIDAB_2651528, AB_2651529, AB_2651530, AB_2651531, AB_2651532, AB_2651533, AB_2651534, AB_2651535, AB_2651536, AB_2651537, AB_2651538, AB_2651527

Resources for DcTRAIL-R1 (TNFRH1) Antibody, anti-mouse, REAfinity™

Certificates

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References for DcTRAIL-R1 (TNFRH1) Antibody, anti-mouse, REAfinity™

Publications

  1. Ikeda, T. et al. (2010) Dual effects of TRAIL in suppression of autoimmunity: the inhibition of Tʜ1 cells and the promotion of regulatory T cells. J. Immunol. 185(9): 5259-5267

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