Clone:
REA757
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
CLECSF8, MCL, CLEC-6

Specifications for CLEC4D (CLECSF8) Antibody, anti-human, REAfinity™

Overview

Clone REA757 recognizes the human CLEC4D antigen, a cell-surface receptor that belongs to the human calcium-dependent lectin family (C-type lectin), also known as CLECSF8, CLEC-6, or MCL. CLEC4D is expressed in a low level in peripheral blood leukocytes, in bone marrow, and spleen. It is mainly found in monocytes and macrophage and seems to be up-regulated by IL-6, IL-10, TNF-α, and IFN-γ.
Additional information: Clone REA757 displays negligible binding to Fc receptors.

Alternative names

CLECSF8, MCL, CLEC-6

Detailed product information

Technical specifications

CloneREA757
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (S), human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman
AntigenCLEC4D (CLECSF8)
Alternative names of antigenCLECSF8, MCL, CLEC-6
Molecular mass of antigen [kDa]25
Distribution of antigenstem cells, leukemia cells, bone marrow, spleen
Entrez Gene ID338339
RRIDAB_2651428, AB_2651429, AB_2651430, AB_2651431, AB_2651432, AB_2651433, AB_2651434, AB_2651435, AB_2651436, AB_2651437, AB_2651438, AB_2651427

Resources for CLEC4D (CLECSF8) Antibody, anti-human, REAfinity™

Certificates

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References for CLEC4D (CLECSF8) Antibody, anti-human, REAfinity™

Publications

  1. Arce, I. et al. (2004) The human C-type lectin CLECSF8 is a novel monocyte/macrophage endocytic receptor. Eur. J. Immunol. 34(1): 210-220
  2. Flornes, L. M. et al. (2004) Identification of lectin-like receptors expressed by antigen presenting cells and neutrophils and their mapping to a novel gene complex. Immunogenetics 56(7): 506-517

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