Clone:
REAL760
Type of antibody:
Releasable fluorochromes, Primary antibodies, Recombinant antibodies
Applications:
MICS, IHC, IF
Alternative names:
Leu-1, T1, Ly-1, Tp67

Specifications for CD5 Antibody, anti-human, REAdye_lease™

Overview

Clone REAL760 is an antibody fragment derived from the full CD5 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity.
Clone REAL760 recognizes the human CD5 antigen, a 67 kDa single-chain transmembrane glycoprotein also known as T1 or Leu-1. It is expressed on most thymocytes, the majority of peripheral T cells, a subpopulation of B cells, and B cell chronic lymphocytic leukemia (B-CLL) cells. CD5 is a receptor for the B cell antigen CD72 and plays a role in T cell activation.
For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675).

Alternative names

Leu-1, T1, Ly-1, Tp67

Detailed product information

Technical specifications

CloneREAL760
Clonalitymonoclonal
Isotype controlControl Antibody
Hostcell line
Type of antibodyReleasable fluorochromes, Primary antibodies, Recombinant antibodies
Specieshuman
AntigenCD5
Alternative names of antigenLeu-1, T1, Ly-1, Tp67
Distribution of antigenB cells, lymphocytes, T cells, thymocytes
RRIDAB_2857733

Resources for CD5 Antibody, anti-human, REAdye_lease™

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

References for CD5 Antibody, anti-human, REAdye_lease™

Publications

  1. Knapp, W. et al. (eds) Leukocyte Typing IV Oxford, Oxford University Press
  2. Van de Velde, H. et al. (1991) The B-cell surface protein CD72/Lyb-2 is the ligand for CD5. Nature 351(6328): 662-665
  3. Osman, N. et al. (1992) Evidence for an association between the T cell receptor/CD3 antigen complex and the CD5 antigen in human T lymphocytes. Eur. J. Immunol. 22(11): 2995-3000
  4. Berland, R. et al. (2002) Origins and functions of B-1 cells with notes on the role of CD5. Annu. Rev. Immunol. 20: 253-300

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