Clone:
MZ18-24A9
Type of antibody:
Primary antibodies
Isotype:
mouse IgG2bκ
Applications:
FC, MICS, IF, IHC
Alternative names:
ITGA4, IA4, VLA-4α

Specifications for CD49d Antibody, anti-human

Overview

CD49d, also known as the α4 integrin chain or VLA-4α chain, is a 150 kDa cell adhesion protein that is directly involved in mononuclear leukocyte trafficking. Dimerized with β7 integrin, the resulting α4β7 integrin binds VCAM-1 (CD106), MAdCAM-1, and fibronectin to facilitate the rolling of leukocytes along vascular epithelium. In T cells, on ligation of MAdCAM-1, α4β7 integrin also provides costimulation of T cell receptor/CD3–mediated signaling.
CD49d is expressed on most mononuclear leukocytes, both in circulation or in lymphoid or other tissues, as well as on eosinophils and basophils.

Alternative names

ITGA4, IA4, VLA-4α

Detailed product information

Technical specifications

CloneMZ18-24A9
Clonalitymonoclonal
Isotypemouse IgG2bκ
Isotype controlIsotype Control Antibody, mouse IgG2b
Hostmouse
Type of antibodyPrimary antibodies
Specieshuman, non-human primate
Cross-reactivity
rhesus monkey (
Macaca mulatta
)
,
cynomolgus monkey (
Macaca fascicularis
)
AntigenCD49d
Alternative names of antigenITGA4, IA4, VLA-4α
Molecular mass of antigen [kDa]111
Distribution of antigenB cells, dendritic cells, Langerhans cells, lymphocytes, macrophages, mast cells, monocytes, myeloid leukemia cells, NK cells, red blood cells, T cells, basophils, eosinophils, myeloid dendritic cells, thymocytes, cardiac muscle, pancreas, skeletal muscle, smooth muscle
Entrez Gene ID3676
RRIDAB_2801974, AB_2819606, AB_2819591, AB_2802066, AB_2802060, AB_2811419, AB_2811407, AB_2857763, AB_2857751, AB_2660798, AB_1036220, AB_1036216, AB_2801995

Resources for CD49d Antibody, anti-human

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

Related products for
CD49d Antibody, anti-human

4 products available

Seems like you are coming from USA!
Do you want to visit our website in your country?