Clone:
FM276
Type of antibody:
Primary antibodies
Isotype:
mouse IgG2bκ
Applications:
FC, MICS, IF, IHC
Alternative names:
4Ig-B7-H3, B7-H3, B7RP-2

Specifications for CD276 Antibody, anti-human

Overview

Clone FM276 reacts with human CD276 (B7-H3), a type I transmembrane protein expressed at low levels in human liver, lung, bladder, testis, prostate, breast, placenta, lymphoid organs, and many human cancers. Surface expression can be induced on T cells, natural killer cells, and macrophages as well as on dendritic cells (DC) by IFN-γ and on monocytes by granulocyte macrophage colony-stimulating factor (GM-CSF) and interleukin 4 (IL-4). B7-H3 has been shown to function as costimulatory molecule for T cell activation by inducing T cell proliferation and IFN-γ production.

Alternative names

4Ig-B7-H3, B7-H3, B7RP-2

Detailed product information

Technical specifications

CloneFM276
Clonalitymonoclonal
Isotypemouse IgG2bκ
Isotype controlIsotype Control Antibody, mouse IgG2b
Hostmouse
Type of antibodyPrimary antibodies
Specieshuman
AntigenCD276
Alternative names of antigen4Ig-B7-H3, B7-H3, B7RP-2
Molecular mass of antigen [kDa]54
Distribution of antigenB cells, dendritic cells, epithelial cells, monocytes, NK cells, T cells, heart, liver, pancreas, placenta, small intestine
Entrez Gene ID80381
RRIDAB_2784099, AB_2819600, AB_2819585, AB_2661014, AB_2661015, AB_2661016, AB_2661017, AB_2661018, AB_2661019, AB_2661020, AB_2661021, AB_10830705, AB_2784100

Resources for CD276 Antibody, anti-human

Certificates

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