Clone:
REA331
Type of antibody:
Recombinant antibodies, Primary antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
ADAM8, CD156, MS2

Specifications for CD156a (ADAM8) Antibody, anti-human, REAfinity™

Overview

Clone REA331 recognizes the human CD156a antigen, a single-pass type I transmembrane protein which is also known as disintegrin or metalloproteinase domain-containing protein 8 (ADAM8). The ADAM family members are membrane-anchored proteins with wide ranging functions, including proteolytic cleavage of cell surface molecules, cell fusion, cell adhesion, and intracellular signaling. CD156a is expressed mainly in cells of the immune system, such as monocytes, neutrophils, eosinophils, dendritic cells, and B cells. As for most ADAM family members, CD156a is involved in ectodomain shedding of membrane proteins like CD23 and L-selectin and is linked to allergic inflammation and neurodegeneration.
Additional information: Clone REA331 displays negligible binding to Fc receptors.

Alternative names

ADAM8, CD156, MS2

Detailed product information

Technical specifications

CloneREA331
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (S), human IgG1
Hostcell line
Type of antibodyRecombinant antibodies, Primary antibodies
Specieshuman
AntigenCD156a (ADAM8)
Alternative names of antigenADAM8, CD156, MS2
Molecular mass of antigen [kDa]87
Distribution of antigendendritic cells, B cells, monocytes, eosinophils, neutrophils
Entrez Gene ID101
RRIDAB_2655298, AB_2655299, AB_2655300, AB_2655297

Resources for CD156a (ADAM8) Antibody, anti-human, REAfinity™

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

References for CD156a (ADAM8) Antibody, anti-human, REAfinity™

Publications

  1. Koller, G. et al. (2009) ADAM8/MS2/CD156, an emerging drug target in the treatment of inflammatory and invasive pathologies Curr. Pharm. Des. 15(20): 2272-2281
  2. Yoshiyama, K. et al. (1997) CD156 (human ADAM8): expression, primary amino acid sequence, and gene location Genomics 41(1): 56-62
  3. Matsuno, O. et al. (2008) ADAM8 in allergy. Inflamm. Allergy Drug Targets 7(2): 108-112

Related products for
CD156a (ADAM8) Antibody, anti-human, REAfinity™

2 products available

Seems like you are coming from USA!
Do you want to visit our website in your country?