Clone:
VIMC6
Type of antibody:
Primary antibodies
Isotype:
mouse IgM
Applications:
FC, MICS, IF, IHC, ICC
Alternative names:
FUT4, ELFT, FCT3A, FUC-TIV, FUTIV, Lex, SSEA-1, Lewis X

Specifications for CD15 Antibody, anti-human

Overview

The CD15 antibody recognizes the CD15 antigen which is expressed on human myelomonocytic cells. It is present on neutrophils, eosinophils, and some monocytes, masked on basophils, but not on lymphocytes. The antigen is also expressed on Hodgkin/Reed-Sternberg cells.
The CD15 antibody recognizes the carbohydrate structure 3-fucosyl-N-acetyl-lactosamine. This structure is also known as stage specific embryonic antigen 1 (SSEA-1) and a common surface marker for pluripotency on mouse ES and iPS cells. On human cells in contrast, SSEA-1 is expressed only on early differentiating cells. The CD15 antibody recognizes the SSEA-1 antigen in both species. For applications in ES and iPS research, the dilution recommended in the data sheet may need adjustment.

Alternative names

FUT4, ELFT, FCT3A, FUC-TIV, FUTIV, Lex, SSEA-1, Lewis X

Detailed product information

Technical specifications

CloneVIMC6
Clonalitymonoclonal
Isotypemouse IgM
Isotype controlIsotype Control Antibody, mouse IgM
Hostmouse
Type of antibodyPrimary antibodies
Specieshuman
AntigenCD15
Alternative names of antigenFUT4, ELFT, FCT3A, FUC-TIV, FUTIV, Lex, SSEA-1, Lewis X
Distribution of antigenB cells, T cells, epithelial cells, granulocytes, Langerhans cells, monocytes, myeloid leukemia cells, basophils, eosinophils, neutrophils, cancer stem cells, bone marrow, brain, breast, kidney, lung
RRIDAB_2726167, AB_2733764, AB_2733765, AB_2733338, AB_2733339, AB_2733930, AB_2733931, AB_2819370, AB_2819367, AB_2733200, AB_2733201, AB_2733025, AB_2733026, AB_2751181, AB_2751115, AB_2726444

Resources for CD15 Antibody, anti-human

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

References for CD15 Antibody, anti-human

Publications

  1. Choi, K.-D. et al. (2011) Hematopoietic differentiation and production of mature myeloid cells from human pluripotent stem cells. Nat. Protoc. 6(3): 296-313

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