25 years ago, Miltenyi Biotec developed the first MACS® Columns that enabled scientists to perform magnetic cell separation in their own labs. Since then, this technology has been continuously optimized and its applications have become more user-friendly. Miltenyi Biotec’s MultiMACS X devicenow allows fully automated performance of all steps, as well as standardized handling of large volumes, high cell numbers, or up to 24 samples in parallel. This process enables the user to continue working with the isolated cell type of interest after just 40 minutes.
Starting material for cell separation can be various blood products, mononuclear cells from peripheral blood, as well as dissociated tissues. All of these samples can be subjected to positive cell isolation as well as depletion strategies. Like most of Miltenyi Biotec’s equipment, the MultiMACS X device reduces workload in the lab substantially. “An intuitively operated touchscreen ensures easy handling while the fully automated cell separation procedure saves valuable manpower and provides reliable and reproducible results,” states Dr. Oliver Schilling, Senior Project Leader, MultiMACS X Development Team at Miltenyi Biotec.
Thanks to its optimized, compact design, the MultiMACS X is easy to integrate into any lab and can be used either as a stand-alone-device or as a module in a fully automated cell processing system. “With the MultiMACS X, we have succeeded in developing a device that offers flexible and versatile applications and therefore can be used in the pharma or biotech industry as well as in routine labs “, says Dr. Schilling.
Cell labeling and separation with the MultiMACS X instrument is based on MACS Technology, which has been cited in more than 20.000 publications. This technology represents the gentlest way of separating cells available on the market and can be applied to nearly any cell type. This is made possible by combining Miltenyi Biotec equipment with the superparamagnetic MACS MicroBeads and the steep magnetic gradient of the MACS Columns.
For more information regarding application options as well as technical details please see www.miltenyibiotec.com/multimacsx.
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November 7–11, 2017 Annual Meeting Society for Neuroscience (Sfn), Washington DC, USA
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About Miltenyi Biotec
Miltenyi Biotec is a global provider of products and services that advance biomedical research and cellular therapy. The company’s innovative tools support research at every level, from basic research to translational research to clinical application. This integrated portfolio enables scientists and clinicians to obtain, analyze, and utilize the cell. Miltenyi Biotec’s technologies cover techniques of sample preparation, cell isolation, cell sorting, flow cytometry, cell culture, molecular analysis, and preclinical imaging. Their more than 25 years of expertise spans research areas including immunology, stem cell biology, neuroscience, and cancer, and clinical research areas like hematology, graft engineering, and apheresis. In their commitment to the scientific community, Miltenyi Biotec also offers comprehensive scientific support, consultation, and expert training. Today, Miltenyi Biotec has more than 2,000 employees in 25 countries – all dedicated to helping researchers and clinicians around the world make a greater impact on science and health. For more information please visitwww.miltenyibiotec.com .
Dr. Christian Stern