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We offer comprehensive solutions for each step of your research with neural cells from the adult brain.
Our adult brain workflow offers a fast, easy solution to isolate and analyze neural cells from adult rodent brain (>P7). Using the Adult Brain Dissociation Kit, mouse and rat with our gentleMACS™ Octo Dissociator with Heaters, gently dissociates brain tissue obtaining highly pure and viable neural cells. Your neural cells of interest can then be isolated with our MicroBeads. These isolated cells are ready for downstream applications, including cell cultivation or analysis with optimized neural media and specific antibodies.
Dissociation of adult brain tissue is fast and easy with our dissociation kits that are made especially for mice and rats older than P7. Together with the gentleMACS Octo Dissociator with Heaters, neural cells are processed gently and efficiently. The additional debris removal and erythrocyte lysis steps of the Adult Brain Dissociation Kit help to purify the neural cell population. For cancer research, we offer the Brain Tumor Dissociation Kit, which is particularly suited for tumor tissue.
To isolate specific neural cell types, we offer a wide range of MicroBeads for magnetic isolation of astrocytes, microglia, oligodendrocytes, and neurons. For neurons, we developed the Adult Neuron Isolation Kit. Through depletion of all non-neuronal cells, neurons remain untouched and thereby undergo a very gentle cell separation, which results in a high viability and purity.
Cells processed with our adult brain workflow are compatible with many downstream applications:
Using our adult brain workflow, your neural cells are gently isolated for downstream applications, including single-cell analysis.
Single-cell analysis of both cell populations showed the main glial subtypes in the unseparated neural cell population and several neuronal subpopulations in the isolated neurons fraction. Single-cell analysis of unseparated neural cells and isolated neurons:
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