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Miltenyi Biotec distribution:
As a global market leader with numerous subsidiaries and distributors, Miltenyi Biotec is committed to providing our customers around the world with the highest quality products. In addition to direct selling in more than 20 countries in North America, Europe and Asia/Pacific, Miltenyi Biotec also provides support for our customers through an extensive distributor network covering dozens of additional countries.
As a global market leader with numerous subsidiaries and distributors, Miltenyi Biotec is committed to providing our customers around the world with the highest quality products. In addition to direct selling in more than 20 countries in North America, Europe and Asia/Pacific, Miltenyi Biotec also provides support for our customers through an extensive distributor network covering dozens of additional countries.
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Instrument
DNA content dyes
Hoechst 33342 Staining Solution (live cells)
DRAQ5 Staining Solution (live cells)
Propidium Iodide Solution (dead cells)
7-AAD Staining Solution (dead cells
DAPI Staining Solution (dead cells)
CyTrak™ Orange Staining Solution (dead cells)
Antibodies
Anti-PCNA antibodies, human, mouse, rat
Anti-Ki-67 antibodies, human and mouse
Different proliferation- and cell cycle-related antigens have been described, allowing for the evaluation of cell kinetic parameters by detecting the expression of these antigens.
Cyclins are a family of proteins that control the progression of cells through the cell cycle by activating cyclin-dependent kinase (CDK) enzymes. The most important cyclins involved in cell cycle processes are listed below.
Protein | Function | Inhibitory protein |
Cyclin A | Control of S phase in complex with Cdk1 or Cdk2 | Cdk1 or Cdk2 |
Cyclin B | Control of G2/M phase in complex with Cdk1 | Cdk1 |
Cyclin D | Control of G1 phase in complex with Cdk4 or Cdk6; Regulation of Rb/E2F transcription | Cdk4 or Cdk6 |
Cyclin E | Control of G1-S phase in complex with Cdk2; Regulation of Rb/E2F transcription | Cdk2 |
Cyclin H | Cdk-activating kinase and RNAPII transcription in complex with Cdk7 | Cdk7 |
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