MACS GMP T Cell TransAct has been developed in the context of TexMACS GMP Medium. Therefore, only this combination can ensure highest performance. Additionally, MACS GMP Recombinant Cytokines, such as IL-2, IL-7, and IL-15 are used within the manufacturing process of T cells. For the GMP-compliant transduction of T cells, an automated process has been established on the CliniMACS Prodigy, e.g., to generate CAR-T cells. To standardize this process an initial enrichment step with the CliniMACS CD4 Reagent, CliniMACS CD8 Reagent, or CliniMACS CD62L Reagent is recommended.