Clone:
11PB6
Type of antibody:
Primary antibodies
Isotype:
mouse IgG1κ
Applications:
FC
Alternative names:
KIR2DL1, KIR-K64, KIR221, NKAT, NKAT-1, p58.1, KIR2DS1

Specifications for CD158a/h (KIR2DL1/DS1) Antibody, anti-human

Overview

Clone 11PB6, also referred to as EB6, recognizes CD158a (KIR2DL1) and CD158h (KIR2DS1), two members of the killer immunoglobulin-like receptor (KIR) family expressed on CD56
dim
CD16
+
natural killer (NK) cells and CD8
+
T cells. Findings also showed reactivity of 11PB6 with KIR2DL3*005.
CD158a (KIR2DL1) is involved in the transduction of an inhibitory signal whereas CD158h (KIR2DS1) is an activating receptor. The ligands of CD158a (KIR2DL1) are HLA-Cw4 and related molecules.

Alternative names

KIR2DL1, KIR-K64, KIR221, NKAT, NKAT-1, p58.1, KIR2DS1

Detailed product information

Technical specifications

Clone11PB6
Clonalitymonoclonal
Isotypemouse IgG1κ
Isotype controlIsotype Control Antibody, mouse IgG1
Hostmouse
Type of antibodyPrimary antibodies
Specieshuman
AntigenCD158a/h (KIR2DL1/DS1)
Alternative names of antigenKIR2DL1, KIR-K64, KIR221, NKAT, NKAT-1, p58.1, KIR2DS1
Molecular mass of antigen [kDa]36
Distribution of antigenNK cells
Entrez Gene ID3802
RRIDAB_2733621, AB_2857764, AB_2857752, AB_2660573, AB_871607, AB_2660575, AB_2660576, AB_871605, AB_871603, AB_2733620

Resources for CD158a/h (KIR2DL1/DS1) Antibody, anti-human

Documents and Protocols

App notes/customer reports

Cross-reactivity of KIR antibodies

References for CD158a/h (KIR2DL1/DS1) Antibody, anti-human

Publications

  1. Falco, M. et al. (2010) Combined genotypic and phenotypic killer cell Ig-like receptor analyses reveal KIR2DL3 alleles displaying unexpected monoclonal antibody reactivity: identification of the amino acid residues critical for staining. J. Immunol. 185: 433-441

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