Clone:
DX9
Type of antibody:
Primary antibodies
Isotype:
mouse IgG1κ
Applications:
FC
Alternative names:
KIR3DL1, NKB1, NKB1B, p70

Specifications for CD158e (KIR3DL1) Antibody, anti-human

Overview

Clone DX9 recognizes CD158e (KIR3DL1), a member of the killer immunoglobulin-like receptor (KIR) family expressed on CD56
dim
CD16
+
natural killer (NK) cells and CD8
+
T cells. KIRs contribute to the regulation of NK cell-mediated cytotoxicity. They are monomeric receptors possessing high allelic polymorphism with either 2 or 3 Ig-like extracellular domains. According to the length of their cytoplasmic tail, KIRs can be further subdivided into inhibitory KIRs and activating KIRs (KIR2DS or KIR3DS). KIR3DL1 provides an inhibitory signal of NK cell lytic activity upon interaction with its specific ligand, HLA-Bw4.

Alternative names

KIR3DL1, NKB1, NKB1B, p70

Detailed product information

Technical specifications

CloneDX9
Clonalitymonoclonal
Isotypemouse IgG1κ
Isotype controlIsotype Control Antibody, mouse IgG1
Hostmouse
Type of antibodyPrimary antibodies
Specieshuman
AntigenCD158e (KIR3DL1)
Alternative names of antigenKIR3DL1, NKB1, NKB1B, p70
Molecular mass of antigen [kDa]47
Distribution of antigenNK cells, T cells
Entrez Gene ID3811
RRIDAB_2819505, AB_2857614, AB_2857602, AB_871615, AB_2660198, AB_871612, AB_2660199, AB_10829778, AB_10829941, AB_2660202, AB_2660203, AB_871613, AB_871611, AB_2819540

Resources for CD158e (KIR3DL1) Antibody, anti-human

References for CD158e (KIR3DL1) Antibody, anti-human

Publications

  1. Farag, S. S. et al. (2002) Natural killer cell receptors: new biology and insights into the graft-versus-leukaemia effect. Blood 100(6): 1935-1947
  2. Hsu, K. et al. (2002) The killer cell immunoglobin-like (KIR) genomic region: gene-order, haplotypes and allelic polymorphism. Immunol. Rev. 190: 40-52
  3. Selvakumar, A. et al. (1997) Polymorphism and domain variability of human killer cell inhibitory receptors. Immunol. Rev. 155: 183-196

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