Clone:
REA1034
Type of antibody:
Recombinant antibodies, Primary antibodies
Isotype:
recombinant human IgG1
Applications:
ICFC

Specifications for IL-6 Antibody, anti-mouse, REAfinity™

Overview

Clone REA1034 recognizes the interleukin 6 (IL-6) antigen, which is originally identified as a B cell differentiation factor. IL-6 is a multifunctional cytokine, which regulates immune responses, hematopoiesis, acute phase responses, and inflammatory reactions. It induces the terminal maturation of activated B cells into antibody-secreting plasma cells and acts in synergy with IL-3 to support the proliferation of hematopoietic stem cells. IL-6 is produced by many cell types, such as monocytes, fibroblasts, endothelial cells, eosinophils, and T cells. Disturbed IL-6 production has been associated with pathological processes, including inflammatory autoimmune diseases and cancer.
Additional information: Clone REA1034 displays negligible binding to Fc receptors.

Detailed product information

Technical specifications

CloneREA1034
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hostcell line
Type of antibodyRecombinant antibodies, Primary antibodies
Speciesmouse
AntigenIL-6
Molecular mass of antigen [kDa]22
Distribution of antigenmonocytes, T cells, endothelial cells, fibroblasts, eosinophils
Entrez Gene ID16193
RRIDAB_2727944, AB_2727996, AB_2727945, AB_2727997, AB_2727946, AB_2727998, AB_2727947, AB_2727995

Resources for IL-6 Antibody, anti-mouse, REAfinity™

Certificates

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