Clone:
MAR-1
Type of antibody:
Primary antibodies, Functional-grade antibodies
Isotype:
hamster IgG
Applications:
FA, FC
Alternative names:
FCER1A, FcERI, Fce1a, Fcr-5

Specifications for FcεRIα Antibody, anti-mouse

Overview

Clone MAR-1 detects the alpha subunit of the murine high-affinity Fc receptor for IgE. The receptor is composed of one alpha-, one beta-, and two disulfid-linked gamma subunits, of which the alpha subunit binds IgE. FcεRIα is expressed on mast and basophilic cells and is up-regulated in the presence of IgE. The FcεRI complex plays an important role in triggering IgE-mediated allergic reactions.

Alternative names

FCER1A, FcERI, Fce1a, Fcr-5

Detailed product information

Technical specifications

CloneMAR-1
Clonalitymonoclonal
Isotypehamster IgG
Hosthamster
Type of antibodyPrimary antibodies, Functional-grade antibodies
Speciesmouse
AntigenFcεRIα
Alternative names of antigenFCER1A, FcERI, Fce1a, Fcr-5
Molecular mass of antigen [kDa]26
Entrez Gene ID14125
RRIDAB_2660610, AB_2660611, AB_2660612, AB_2660613, AB_2660614, AB_2660615, AB_2660616, AB_10828823

Resources for FcεRIα Antibody, anti-mouse

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

References for FcεRIα Antibody, anti-mouse

Publications

  1. Kojima, T. et al. (2007)
    Mast cells and basophils are selectively activated
    in vitro
    and
    in vivo
    through CD200R3 in an IgE-independent manner.
    J. Immunol. 179: 7093-7100
  2. Yamaguchi, M. et al. (2001) Regulation of mouse mast cell surface Fc epsilon RI expression by dexamethasone. Int. Immunol. 13: 843-851
  3. Metzger, H. et al. (1989) The receptor with high affinity for IgE. Ciba Found. Symp. 147: 93-113

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