Clone:
REAL180
Type of antibody:
Releasable antibodies, Primary antibodies, Recombinant antibodies
Applications:
FC, MICS, IHC, IF
Alternative names:
ICAM-1, Ly-47, MALA-2

Specifications for CD45 Antibody, anti-mouse,
REAlease
®

Overview

Clone REAL180 is an antibody fragment derived from the full CD45 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAlease Complex to bind markers with high avidity.
Clone REAL180 recognizes the mouse CD45 antigen (Ly-5, leukocyte common antigen) which is expressed at high levels on all cells of hematopoietic origin except for erythrocytes. Clone REAL180 reacts with all CD45 isoforms. CD45 (Ly-5, leukocyte common antigen) can be used to discriminate leukocytes from non-hematopoietic cells.
The REAlease Kits consist of the respective fluorochrome-conjugated REAlease Complexes and the REAlease Support Kit for removal of the REAlease Complexes and optional relabeling with different fluorochrome-conjugated REAlease Complexes.

Alternative names

ICAM-1, Ly-47, MALA-2

Detailed product information

Technical specifications

CloneREAL180
Clonalitymonoclonal
Isotype controlControl Antibody
Hostcell line
Type of antibodyReleasable antibodies, Primary antibodies, Recombinant antibodies
Speciesmouse
AntigenCD45
Alternative names of antigenICAM-1, Ly-47, MALA-2
Distribution of antigenmacrophages, monocytes, lymphocytes, endothelial cells, dendritic cells
RRIDAB_2784196, AB_2751294, AB_2784195, AB_2784194, AB_2784197, AB_2811685, AB_2751244

Resources for CD45 Antibody, anti-mouse,
REAlease
®

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

References for CD45 Antibody, anti-mouse,
REAlease
®

Publications

  1. Siu, G. et al. (1989) Isolation of the murine intercellular adhesion molecule 1 (ICAM-1) gene. ICAM-1 enhances antigen-specific T cell activation. J. Immunol. 143(11): 3813-3820
  2. Fine, J. S. et al. (1991) The role of LFA-1/ICAM-1 interactions during murine T lymphocyte development. J. Immunol. 147(9): 2852-2859
  3. Driessens, M. H. et al. (1996) Inhibition and stimulation of LFA-1 and Mac-1 functions by antibodies against murine CD18. Evidence that the LFA-1 binding sites for ICAM-1, -2, and -3 are distinct. J. Leukoc. Biol. 60(6): 758-765

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REAlease
®

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