Clone:
REA1074
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC, MICS, IF, IHC
Alternative names:
ITGB1, FNRB, GPIIa

Specifications for CD29 Antibody, anti-mouse/rat, REAfinity™

Overview

Clone REA1074 reacts with mouse and rat CD29 antigen, a 110–120 kDa integrin family member, also known as integrin ß1. Integrins are cell-surface receptors, expressed as heterodimers essential in various processes mediating intercellular or cell-matrix interaction. CD29 associates non‐covalently with the alpha integrins CD49a–f to form the VLA-1 through VLA-6, and CD51 to form αvß1 complexes. CD29 is broadly expressed on various tissues, including leukocytes, endothelial cells, and epithelial cells.
Additional information: Clone REA1074 displays negligible binding to Fc receptors.

Alternative names

ITGB1, FNRB, GPIIa

Detailed product information

Technical specifications

CloneREA1074
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Speciesmouse, rat
AntigenCD29
Alternative names of antigenITGB1, FNRB, GPIIa
Molecular mass of antigen [kDa]86
Distribution of antigenendothelial cells, fibroblasts, granulocytes, leukocytes, mast cells, platelets, red blood cells, T cells, epithelial cells, ES and iPS cells, mesenchymal stem cells
Entrez Gene ID16412
RRIDAB_2751649, AB_2751650, AB_2751603, AB_2751651

Resources for CD29 Antibody, anti-mouse/rat, REAfinity™

Certificates

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References for CD29 Antibody, anti-mouse/rat, REAfinity™

Publications

  1. Noto, K. et al. (1995) Identification and functional characterization of mouse CD29 with a mAb. Int. Immunol. 7: 835-842
  2. Noto, K. et al. (2001) Differential effects of CD18, CD29, and CD49 integrin subunit inhibition on neutrophil migration in pulmonary inflammation. J. Immunol. 166(5): 3484-3490
  3. Chacko, S. M. et al. (2009) Myocardial oxygeneration and functional recovery in infarct rat hearts transplanted with mesenchymal stem cells. Am. J. Physiol. Heart Circ. Physiol. 296(5): H1263-1273

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