Clone:
REA777
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
ICFC, MICS, IF, IHC
Alternative names:
LAMP-1, LAMP1

Specifications for CD107a (LAMP-1) Antibody, anti-mouse, REAfinity™

Overview

Clone REA777 recognizes the mouse CD107a antigen, a 110–140 kDa type I membrane protein which is heavily glycosylated from a 40 kDa core protein. CD107a, also known as lysosome-associated membrane protein 1 (LAMP-1), is a ligand for galaptin, an S-type lectin, and is located on lysosomal membrans that can be used to distinguish lysosomes from other organelles. It is expressed on epithelial cells, macrophages, as well as on cells of different organs in mice.
Additional information: Clone REA777 displays negligible binding to Fc receptors.

Alternative names

LAMP-1, LAMP1

Detailed product information

Technical specifications

CloneREA777
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Speciesmouse
AntigenCD107a (LAMP-1)
Alternative names of antigenLAMP-1, LAMP1
Molecular mass of antigen [kDa]42
Distribution of antigendendritic cells, epithelial cells, granulocytes, macrophages, T cells, endothelial cells, platelets, neutrophils
Entrez Gene ID16783
RRIDAB_2654464, AB_2654465, AB_2654466, AB_2654467, AB_2654468, AB_2654469, AB_2654470, AB_2654463

Resources for CD107a (LAMP-1) Antibody, anti-mouse, REAfinity™

Certificates

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to search for Certificates of Analysis (CoA) by lot number.

References for CD107a (LAMP-1) Antibody, anti-mouse, REAfinity™

Publications

  1. Chen, J. W. et al. (1985) Identification of two lysosomal membrane glycoproteins. J. Cell Biol. 101: 85-95
  2. Chen, J. W. et al. (1986) Lysosomal membrane glycoproteins: properties of LAMP-1 and LAMP-2. Biochem. Soc. Symp. 51: 97-112
  3. Arterburn, L. M. et al. (1990) The disulfide structure of mouse lysosome-associated membrane protein 1. J. Biol. Chem. 265(13): 7419-7423

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