Clone:
REA1152
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
MICS, IF, IHC
Alternative names:
Beta-III tubulin, Tubulin beta-3 chain, Tubulin beta-4 chain, Tubulin beta-III, TUBB3, TUBB4

Specifications for β-Tubulin 3 Antibody, anti-human/mouse, REAfinity™

Overview

Clone REA1152 recognizes the β-Tubulin 3, a neuron specific marker, which is an early marker to signal commitment in primitive neuroepithelium. Tubulin is a dimer composed of an a and a b tubulin molecule. Tubulin is the major component of the eukaryotic cytoskeleton, which is involved in mitosis, cytokinesis, intracellular transport of vesicles and organelles, and DNA segregation. In certain cancer cells β-Tubulin 3 exoression is increased. REA1152 detects only isoform 3 but no other beta tubulin isotypes.
Additional information: Clone REA1152 displays negligible binding to Fc receptors.

Alternative names

Beta-III tubulin, Tubulin beta-3 chain, Tubulin beta-4 chain, Tubulin beta-III, TUBB3, TUBB4

Detailed product information

Technical specifications

CloneREA1152
Clonalitymonoclonal
Isotyperecombinant human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman, mouse, other
Cross-reactivitymammals, chicken
Antigenβ-Tubulin 3
Alternative names of antigenBeta-III tubulin, Tubulin beta-3 chain, Tubulin beta-4 chain, Tubulin beta-III, TUBB3, TUBB4
RRIDAB_2857509, AB_2857508

Resources for β-Tubulin 3 Antibody, anti-human/mouse, REAfinity™

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

References for β-Tubulin 3 Antibody, anti-human/mouse, REAfinity™

Publications

  1. Zhou, J. et al. (2005) Targeting microtubules for cancer chemotherapy. Curr. Med. Chem. 5(1): 65-71
  2. Gunning, P. W. et al. (2015) The evolution of compositionally and functionally distinct actin filaments. J. Cell. Sci. 128(11): 2009-2019

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