Alternative names:
IGF-I

Specifications for Human IGF-1

Overview

IGF-1 stands for insulin-like growth factor 1. Human IGF-1 is a recombinant protein optimized for use in cell culture, differentiation studies, and functional assays.

Applications

Human IGF-1 can be used for a variety of applications including:
  • Cell culture neurobiology.
  • Differentiation and proliferation of myeloid cells.

Alternative names

IGF-I

Detailed product information

Background information

Insulin-like growth factor 1 (IGF-1), also known as somatomedin-C, is a protein that stimulates the proliferation and survival of various cell types including muscle, bone, and cartilage tissue
in vitro
. It plays an important role in childhood growth and continues to have anabolic effects in adults. IGF-1 belongs to the family of insulin-like growth factors, binds to the IGF-1 receptor, and activates the PI3K/AKT pathway as well as the ERK1/2 pathway. It is mainly produced in the liver and stimulates differentiation and proliferation of myeloid cells together with IL-3.

Biological activity

  • Proliferation of FDC-P1 cells
  • research grade: ≥ 5×
    10
    5
    U/mg

Quality description

Research-grade
cytokines are suitable for a wide variety of cell culture applications. They are sterile-filtered prior to lyophilization. Generally, endotoxin levels are <0.1 ng/μg (<1 EU/μg), and purities are >95%. The biological activity is tested in appropriate bioassays.

Resources for Human IGF-1

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.