Clone:
REA1060
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC, MICS, IF, IHC
Alternative names:
ITGB1, FNRB, GPIIa, MDF2, MSK12, VLA-BETA, VLAB

Specifications for CD29 Antibody, anti-human, REAfinity™

Overview

Clone REA1060 recognizes the human CD29 antigen, a 130 kDa single-pass type I membrane protein. CD29 is also known as integrin β1 or GPIIa. It forms heterodimers with integrins α1-11 and αV to form functional integrin receptors which bind several cell surface and extracellular molecules such as collagen, fibronectin, laminin, VCAM1, cytotactin, osteopontin, epiligrin, thrombospondin, etc. The cytoplasmic domain of CD29 can interact with cytoskeletal proteins and signaling molecules. In humans, CD29 can be found in four different isoforms (β1A, β1B, β1C, β1D).
Additional information: Clone REA1060 displays negligible binding to Fc receptors.

Alternative names

ITGB1, FNRB, GPIIa, MDF2, MSK12, VLA-BETA, VLAB

Detailed product information

Technical specifications

CloneREA1060
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (S), human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman
AntigenCD29
Alternative names of antigenITGB1, FNRB, GPIIa, MDF2, MSK12, VLA-BETA, VLAB
Molecular mass of antigen [kDa]86
Entrez Gene ID3688
RRIDAB_2751459, AB_2751453, AB_2751460, AB_2751454, AB_2751461, AB_2751455

References for CD29 Antibody, anti-human, REAfinity™

Publications

  1. Altruda, F. et al. (1990) A human integrin beta 1 subunit with a unique cytoplasmic domain generated by alternative mRNA processing. Gene 95: 261-266
  2. Shih, D. T. et al. (1993) Structure/function analysis of the integrin beta 1 subunit by epitope mapping. J. Cell Biol. 122(6): 1361-1371
  3. Brakebusch, C. et al. (1997) Genetic analysis of beta1 integrin function: confirmed, new and revised roles for a crucial family of cell adhesion molecules. J. Cell. Sci. 110: 2895-2904

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