Clone:
REA1010
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC, MC
Alternative names:
KIR2DL1, KIR-K64, KIR221, NKAT, NKAT-1, p58.1, KIR2DS1

Specifications for CD158a/h (KIR2DL1/DS1) Antibody, anti-human, REAfinity™

Overview

Clone REA1010 recognizes the human CD158a (KIR2DL1) and CD158h (KIR2DS1) antigens, two members of the killer immunoglobulin-like receptor (KIR) family expressed on CD56
dim
CD16
+
natural killer (NK) cells and CD8
+
T cells. CD158a (KIR2DL1) is involved in the transduction of an inhibitory signal whereas CD158h (KIR2DS1) is an activating receptor. The ligands of CD158a (KIR2DL1) are HLA-Cw4 and related molecules.
Additional information: Clone REA1010 displays negligible binding to Fc receptors.

Alternative names

KIR2DL1, KIR-K64, KIR221, NKAT, NKAT-1, p58.1, KIR2DS1

Detailed product information

Technical specifications

CloneREA1010
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (S), human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman
AntigenCD158a/h (KIR2DL1/DS1)
Alternative names of antigenKIR2DL1, KIR-K64, KIR221, NKAT, NKAT-1, p58.1, KIR2DS1
Molecular mass of antigen [kDa]36
Distribution of antigenNK cells, T cells, CD8+ T cells
Entrez Gene ID3802
RRIDAB_2727794, AB_2727722, AB_2727795, AB_2727723, AB_2727796, AB_2727724, AB_2727725, AB_2727726, AB_2727797, AB_2727727, AB_2801922

Resources for CD158a/h (KIR2DL1/DS1) Antibody, anti-human, REAfinity™

Documents and Protocols

References for CD158a/h (KIR2DL1/DS1) Antibody, anti-human, REAfinity™

Publications

  1. Falco, M. et al. (2010) Combined genotypic and phenotypic killer cell Ig-like receptor analyses reveal KIR2DL3 alleles displaying unexpected monoclonal antibody reactivity: identification of the amino acid residues critical for staining. J. Immunol. 185: 433-441

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