Clone:
REA588
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
ICFC
Alternative names:
PKCtheta

Specifications for PKCθ Antibody, anti-human, REAfinity™

Overview

Clone REA588 recognizes the human PKCθ antigen, which is a member of the protein kinase C (PKC) family of homologous serine/threonine protein kinases that phosphorylate the OH group of serine or threonine. PKCs play a role in the carcinogenesis and maintenance of malignant phenotype. PKCθ transcripts are expressed in hematopoietic tissues and cell lines, including T cells and thymocytes.
Additional information: Clone REA588 displays negligible binding to Fc receptors.

Alternative names

PKCtheta

Detailed product information

Technical specifications

CloneREA588
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (I), human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman
AntigenPKCθ
Alternative names of antigenPKCtheta
Molecular mass of antigen [kDa]82
Distribution of antigenT cells, thymocytes
Entrez Gene ID5588
RRIDAB_2653214, AB_2653215, AB_2653216, AB_2653213

Resources for PKCθ Antibody, anti-human, REAfinity™

Certificates

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References for PKCθ Antibody, anti-human, REAfinity™

Publications

  1. Nishizuka, Y. (1988) The molecular heterogeneity of protein kinase C and its implications for cellular regulation. Nature 334(6184): 661-665
  2. Koivunen, J. et al. (2006) Protein kinase C (PKC) family in cancer progression. Cancer Lett. 235(1): 1-10

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