Clone:
HMJ2-1
Type of antibody:
Primary antibodies
Isotype:
hamster IgG
Applications:
FC
Alternative names:
JAG2, D12Ggc2e, Serh, mJagged2-1, sm

Specifications for Jagged2 Antibody, anti-mouse

Overview

The HMJ2-1 monoclonal antibody recognizes mouse Jagged2, a transmembrane protein also called JAG2. Jagged 2 is one of five Notch receptor ligands expressed on thymic lymphoid and stromal cells, splenic DCs and macrophages but not on B cells. It is reported that Jagged 2 promotes metastasis in lung by increasing the expression of GATA binding factors.

Alternative names

JAG2, D12Ggc2e, Serh, mJagged2-1, sm

Detailed product information

Technical specifications

CloneHMJ2-1
Clonalitymonoclonal
Isotypehamster IgG
Hosthamster
Type of antibodyPrimary antibodies
Speciesmouse
AntigenJagged2
Alternative names of antigenJAG2, D12Ggc2e, Serh, mJagged2-1, sm
Molecular mass of antigen [kDa]132
Entrez Gene ID16450
RRIDAB_2652542, AB_2652543, AB_2652541

Resources for Jagged2 Antibody, anti-mouse

Certificates

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References for Jagged2 Antibody, anti-mouse

Publications

  1. Yang, Y. et al. (2011)
    Treatment of acute myeloid leukemia cells
    in vitro
    with a monoclonal antibody recognizing a myeloid differentiation antigen allows normal progenitor cells to be expressed.
    J. Clin. Invest. 121(4): 1373-1385
  2. Moriyama, Y. et al. (2008) Delta-like 1 is essential for the maintenance of marginal zone B cells in normal mice but not in autoimmune mice. Int. Immunol. 20: 763-773
  3. Sekine, C. et al. (2009) Differential regulation of splenic CD8– dendritic cells and marginal zone B cells by Notch ligands. Int. Immunol. 21: 295-301

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