iNKT Antibody, anti-human

Name: iNKT Antibody, anti-human
Availability: InStock

iNKT Antibody, anti-human

Clone:

6B11

Type of antibody:

Primary antibodies, Functional-grade antibodies

Isotype:

mouse IgG1κ, mouse IgG1

Applications:

FC, FA

Flow cytometry

Conjugate:	PE-Vio 770
Recommended dilution:	1:11
Remark:	Cells should be stained prior to fixation, if formaldehyde is used as a fixative.
Tested:	QC tested
Products used:	130-104-148, 130-104-110

Functional assay

Conjugate:	pure-functional grade
Tested:	during development
Products used:	130-094-865
Type of functional assay:	in vitro iNKT cell activation, in vitro iNKT cell expansion

Specifications for iNKT Antibody, anti-human

Overview

NKT cells represent a distinct lymphocyte population that co-expresses T cell and NK cell surface markers. A subset of human NKT cells, referred to as iNKT cells, expresses an invariant TCR α-chain with certain TCR β-chains (Vα24-Jα18 combined with Vβ11). The iNKT cells are implicated in immunoregulatory processes such as tolerance, host defense, and tumor surveillance.

Detailed product information

Technical specifications

Clone	6B11
Clonality	monoclonal
Isotype	mouse IgG1κ, mouse IgG1
Isotype control	Isotype Control Antibody, mouse IgG1
Host	mouse
Type of antibody	Primary antibodies, Functional-grade antibodies
Species	human, non-human primate
Cross-reactivity	rhesus monkey ( Macaca mulatta ) , cynomolgus monkey ( Macaca fascicularis )
Antigen	iNKT
Distribution of antigen	stem cells, NKT cells
Entrez Gene ID	28659, 28747, 28582, 28581
RRID	AB_10829021, AB_2659824, AB_10828553, AB_2659825, AB_10828344, AB_2659826, AB_2659827, AB_2659828, AB_10829307

Reviews for iNKT Antibody, anti-human

Very Comparable Antibody to Competitors

Anti-iNKT-PE-Vio770, human (130-104-110)

My work involves enumerating iNKT cells in human blood and tissue samples. For this I have wanted to try Miltenyi Biotec's antibody and compare it to other company brands to see if quality was good, as Miltenyi Biotec's products are highly price competitive. Also, I have been using their MACS beads for cell isolation for a few years. Results: I have switched over to Miltenyi Biotec.

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References for iNKT Antibody, anti-human

Publications

Exley, M. et al. (2008) Selective activation, expansion, and monitoring of human iNKT cells with a monoclonal antibody specific for the TCR α-chain CDR3 loop. Eur. J. Immunol. 38: 1756-1766
Montoya, J. C. et al. (2007) Characterization of human invariant natural killer T subsets in health and disease using a novel invariant natural killer T cell-clonotypic monoclonal antibody, 6B11. Immunology 122: 1-14

Applications

Specifications

Specifications for iNKT Antibody, anti-human

Overview

Detailed product information

Technical specifications

Clone	6B11
Clonality	monoclonal
Isotype	mouse IgG1κ, mouse IgG1
Isotype control	Isotype Control Antibody, mouse IgG1
Host	mouse
Type of antibody	Primary antibodies, Functional-grade antibodies
Species	human, non-human primate
Cross-reactivity	rhesus monkey ( Macaca mulatta ) , cynomolgus monkey ( Macaca fascicularis )
Antigen	iNKT
Distribution of antigen	stem cells, NKT cells
Entrez Gene ID	28659, 28747, 28582, 28581
RRID	AB_10829021, AB_2659824, AB_10828553, AB_2659825, AB_10828344, AB_2659826, AB_2659827, AB_2659828, AB_10829307

Reviews

Reviews for iNKT Antibody, anti-human

Very Comparable Antibody to Competitors

Anti-iNKT-PE-Vio770, human (130-104-110)

Write a review

References

References for iNKT Antibody, anti-human

Publications

Exley, M. et al. (2008) Selective activation, expansion, and monitoring of human iNKT cells with a monoclonal antibody specific for the TCR α-chain CDR3 loop. Eur. J. Immunol. 38: 1756-1766
Montoya, J. C. et al. (2007) Characterization of human invariant natural killer T subsets in health and disease using a novel invariant natural killer T cell-clonotypic monoclonal antibody, 6B11. Immunology 122: 1-14

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iNKT Antibody, anti-human

iNKT Antibody, anti-human

Flow cytometry

Functional assay

Specifications for iNKT Antibody, anti-human

Overview

Detailed product information

Technical specifications

Reviews for iNKT Antibody, anti-human

Anti-iNKT-PE-Vio770, human (130-104-110)

References for iNKT Antibody, anti-human

Publications

Specifications for iNKT Antibody, anti-human

Overview

Detailed product information

Technical specifications

Reviews for iNKT Antibody, anti-human

Anti-iNKT-PE-Vio770, human (130-104-110)

References for iNKT Antibody, anti-human

Publications

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