Clone:
REA896
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
ICFC
Alternative names:
ELK1

Specifications for ELK-1 pS383 Antibody, anti-human, REAfinity™

Overview

Clone REA896 recognizes the human transcription factor ELK-1, also known as ETS domain–containing protein ELK-1. ELK-1 is a member of the E twenty-six (Ets) oncogene family that consists of nuclear phosphoproteins, which are involved in many processes, e.g., differentiation, growth, and survival of cells, hematopoiesis, angiogenesis, wound healing, cancer, and inflammation. ELK-1 is a target of ERK1 and ERK2, which are both members of protein kinases, but also of JNK and p38 MAPK, which are all involved in diverse physiopathological forms of neuronal plasticity. ELK-1 is mainly found in brain, and it is strongly expressed in neurons.
Additional information: Clone REA896 displays negligible binding to Fc receptors.

Alternative names

ELK1

Detailed product information

Technical specifications

CloneREA896
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (I), human IgG1
Hosthuman cell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman
AntigenELK-1 pS383
Alternative names of antigenELK1
Molecular mass of antigen [kDa]45
Distribution of antigenneurons, brain
Entrez Gene ID2002
RRIDAB_2726806, AB_2726839, AB_2726807, AB_2726840, AB_2726808, AB_2726838

Resources for ELK-1 pS383 Antibody, anti-human, REAfinity™

Certificates

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References for ELK-1 pS383 Antibody, anti-human, REAfinity™

Publications

  1. Gille, H. et al. (1995) ERK phosphorylation potentiates Elk-1-mediated ternary complex formation and transactivation. EMBO J. 14(5): 951-962
  2. Sharrocks, A. D. (2001) The ETS-domain transcription factor family. Nat. Rev. Mol. Cell Biol. 2(11): 827-837
  3. Besnard, A. et al. (2011) Elk-1 a transcription factor with multiple facets in the brain. Front. Neurosci. 5: 35

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