Clone:
REA939
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
MICS, IF, IHC
Alternative names:
erbB-1, HER1, ERBB, ERBB1, EGFR

Specifications for EGF Receptor Antibody, anti-human, REAfinity™

Overview

Clone REA939 recognizes the human epidermal growth factor receptor (EGFR) antigen. EGFR is a single-pass type I membrane protein which is also known as receptor tyrosine-protein kinase ErbB-1 or HER1. EGFR is expressed in normal cells and overexpressed in many tumor cell lines. It is a critical regulator of many normal cellular processes, including cell growth, differentiation, survival, and migration. The EGFR is also implicated in pathological processes of cellular transformation and oncogenesis due to its overexpression in many types of cancers and its ability to induce morphological transformation of cultured cells and tumor formation in nude mice.
Additional information: Clone REA939 displays negligible binding to Fc receptors.

Alternative names

erbB-1, HER1, ERBB, ERBB1, EGFR

Detailed product information

Technical specifications

CloneREA939
Clonalitymonoclonal
Isotyperecombinant human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman, mouse
Cross-reactivitymouse
AntigenEGF Receptor
Alternative names of antigenerbB-1, HER1, ERBB, ERBB1, EGFR
Distribution of antigenany cell type, tumor cells, placenta

Resources for EGF Receptor Antibody, anti-human, REAfinity™

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

References for EGF Receptor Antibody, anti-human, REAfinity™

Publications

  1. Ullrich, A. et al. (1984) Human epidermal growth factor receptor cDNA sequence and aberrant expression of the amplified gene in A431 epidermoid carcinoma cells. Nature 309(5967): 418-425
  2. Herbst, R. A. (2004) Review of epidermal growth factor receptor biology. Int. J. Radiat.Oncol. Biol. Phys. 59: 21-26

Seems like you are coming from USA!
Do you want to visit our website in your country?