Clone:
REA188
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC, MICS, IF, IHC
Alternative names:
Itga2, BR, α2 integrin, gpIa, HPA-5, VLA-2, VLAA2, CD49b, VLA-2α

Specifications for CD49b Antibody, anti-human, REAfinity™

Overview

Clone REA188 recognizes CD49b, also known as integrin α2 chain. CD49b is single-pass, 150 KDa, type I membrane protein. Together with integrin β1 (CD29), CD49b forms the VLA-2 receptor, which binds ligands such as collagen, fibrinogen, and laminin and thus mediate the attachment of several cell types to extracellular matrix. Expression of CD49b is found on lymphocytes, activated T cells, monocytes, epithelial cells, and platelets.
Additional information: Clone REA188 displays negligible binding to Fc receptors.

Alternative names

Itga2, BR, α2 integrin, gpIa, HPA-5, VLA-2, VLAA2, CD49b, VLA-2α

Detailed product information

Technical specifications

CloneREA188
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (S), human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman
AntigenCD49b
Alternative names of antigenItga2, BR, α2 integrin, gpIa, HPA-5, VLA-2, VLAA2, CD49b, VLA-2α
Molecular mass of antigen [kDa]126
Distribution of antigenmegakaryocytes, monocytes, platelets, T cells
Entrez Gene ID3673
RRIDAB_2857655, AB_2857630, AB_2658459, AB_2658460, AB_2658463, AB_2658464, AB_2658465, AB_2658466, AB_2658467, AB_2658468

Resources for CD49b Antibody, anti-human, REAfinity™

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

References for CD49b Antibody, anti-human, REAfinity™

Publications

  1. Elices, M. J., et al. (1989) The human integrin VLA-2 is a collagen receptor on some cells and a collagen/laminin receptor on others. Proc. Natl. Acad. Sci. U.S.A. 86: 9906-9910

Related products for
CD49b Antibody, anti-human, REAfinity™

3 products available

Seems like you are coming from USA!
Do you want to visit our website in your country?