Clone:
Real755
Type of antibody:
Releasable fluorochromes, Primary antibodies, Recombinant antibodies
Applications:
MICS, IHC, IF
Alternative names:
Ptprc, B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200

Specifications for CD45RB Antibody, anti-human, REAdye_lease™

Overview

Clone REAL755 is an antibody fragment derived from the full CD45RB antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity.
Clone REAL755 recognizes CD45RB, which is a splice variant isoform of CD45, the Leukocyte Common Antigen (LCA). CD45 is a haemopoietic cell specific protein tyrosine phosphatase, and regulates various signalling events through cytokine receptors and in response to cellular adhesion. Expression of CD45RB is found on T cell subset, B cells, monocytes/macrophages, granulocytes and dendritic cells.
For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675).

Alternative names

Ptprc, B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200

Detailed product information

Technical specifications

CloneReal755
Clonalitymonoclonal
Isotype controlControl Antibody
Hosthuman cell line
Type of antibodyReleasable fluorochromes, Primary antibodies, Recombinant antibodies
Specieshuman
AntigenCD45RB
Alternative names of antigenPtprc, B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200
Distribution of antigenB cells, NK cells, myeloid cells, T cells

Resources for CD45RB Antibody, anti-human, REAdye_lease™

Certificates

Please follow this
link
to search for Certificates of Analysis (CoA) by lot number.

References for CD45RB Antibody, anti-human, REAdye_lease™

Publications

  1. Parikh, K. et al. (2009) Extracellular ligation-dependent CD45RB enzymatic activity negatively regulates lipid raft signal transduction. Blood 113: 594-603
  2. Dianzani, U. et al. (1992) Isoform-specific associations of CD45 with accessory molecules in human T lymphocytes. Eur. J. Immunol. 22(2): 365-371

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