Clone:
REA128
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
FC
Alternative names:
OX-2 receptor 3

Specifications for CD200R3 Antibody, anti-mouse, REAfinity™

Overview

Clone REA128 recognizes the human CD200R3 antigen. CD200R is an approximately 33 kDa single-pass type I membrane-protein which is a disulfide-linked dimer on the cell surface. It is reported, that the four different isoforms of CD200R (CD200R1, CD200R2, CD200R3, CD200R4) bind to CD200 (OX-2) as ligand. CD200 is primarily expressed on myeloid cells but also expressed on T and B lymphocytes. The combination of CD200R and CD200 inhibits mast cell degranulation, promotes macrophage activation, and decreases the activation of lymphocytes.
Additional information: Clone REA128 displays negligible binding to Fc receptors.

Alternative names

OX-2 receptor 3

Detailed product information

Technical specifications

CloneREA128
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody, human IgG1
Hosthuman cell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Speciesmouse
AntigenCD200R3
Alternative names of antigenOX-2 receptor 3
Molecular mass of antigen [kDa]31
Distribution of antigenT cells, B cells
Entrez Gene ID74603
RRIDAB_2656119, AB_2656120, AB_2656121, AB_2656122, AB_2656123, AB_2656124, AB_2656125, AB_2656126, AB_2656127, AB_2656118

Resources for CD200R3 Antibody, anti-mouse, REAfinity™

Certificates

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References for CD200R3 Antibody, anti-mouse, REAfinity™

Publications

  1. Gorczynski, R. et al. (2004) CD200 is a ligand for all members of the CD200R family of immunoregulatory molecules. J. Immunol. 172: 7744-7749
  2. Wright, G. J. et al. (2003) Characterization of the CD200 receptor family in mice and humans and their interactions with CD200. J. Immunol. 171: 3034-3046
  3. Rijkers, E. S. et al. (2008) The inhibitory CD200R is differentially expressed on human and mouse T and B lymphocytes. Mol. Immunol. 45(4): 1126-1135

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