Clone:
REA1200
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
ICFC
Alternative names:
DNTT

Specifications for TdT Antibody, anti-human/mouse, REAfinity™

Overview

Clone REA1200 recognizes terminal deoxynucleotidyl transferase (TdT), a template independent, 60 kDa DNA polymerase. TdT catalyzes addition of deoxynucleotides to the 3'-OH terminus of oligonucleotide primer segments. Expression of TdT is found in immature lymphocytes during early differentiation where it is involved in generating antigen receptor diversity by mediating Ig gene rearrangement.
Additional information: Clone REA1200 displays negligible binding to Fc receptors.

Alternative names

DNTT

Detailed product information

Technical specifications

CloneREA1200
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (I), human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman, mouse
AntigenTdT
Alternative names of antigenDNTT
Molecular mass of antigen [kDa]59
Distribution of antigenlymphocytes
Entrez Gene ID1791
RRIDAB_2801948, AB_2801953, AB_2801949, AB_2801950, AB_2801954, AB_2801951, AB_2801952

References for TdT Antibody, anti-human/mouse, REAfinity™

Publications

  1. Fowler, J. D. and Suo, Z. (2006) Biochemical, structural, and physiological characterization of terminal deoxynucleotidyl transferase. Chem. Rev. 106: 2092-2110

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