Clone:
REA701
Type of antibody:
Primary antibodies, Recombinant antibodies
Isotype:
recombinant human IgG1
Applications:
ICFC
Alternative names:
Transcription factor SOX-17, SOX-17

Specifications for Sox17 Antibody, anti-human, REAfinity™

Overview

Clone REA701 recognizes the human Sox17 antigen, a member of the SRY-related HMG-box family of transcription factors, which are implicated in embryogenesis. Sox17 is a transcription regulator that binds target promoter DNA and bends the DNA. Sox17 is found in adult heart, lung, spleen, testis, ovary, placenta, fetal lung, and kidney. In normal gastrointestinal tract, it is preferentially expressed in esophagus, stomach, and small intestine than in colon and rectum.
Additional information: Clone REA701 displays negligible binding to Fc receptors.

Alternative names

Transcription factor SOX-17, SOX-17

Detailed product information

Technical specifications

CloneREA701
Clonalitymonoclonal
Isotyperecombinant human IgG1
Isotype controlREA Control Antibody (I), human IgG1
Hostcell line
Type of antibodyPrimary antibodies, Recombinant antibodies
Specieshuman
AntigenSox17
Alternative names of antigenTranscription factor SOX-17, SOX-17
Molecular mass of antigen [kDa]44
Distribution of antigenother, esophagus, heart, kidney, lung, placenta, ovary, spleen, testicle
Entrez Gene ID64321
RRIDAB_2653493, AB_2653494, AB_2653495, AB_2653496, AB_2653497, AB_2653498, AB_2653492

References for Sox17 Antibody, anti-human, REAfinity™

Publications

  1. Séguin, C. A. et al. (2008) Establishment of endoderm progenitors by SOX transcription factor expression in human embryonic stem cells. Cell Stem Cell 3(2): 182-195
  2. D'Amour, K. A. et al. (2005) Efficient differentiation of human embryonic stem cells to definitive endoderm. Nat. Biotechnol. 23(12): 1534-1541
  3. Katoh, M. (2002) Molecular cloning and characterization of human SOX17. Int. J. Mol. Med. 9(2): 153-157

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