Clone:
MB9-3G8
Type of antibody:
Primary antibodies
Isotype:
rat IgG1
Applications:
FC
Alternative names:
PROM1, AC133, CD133

Specifications for Prominin-1 Antibody, anti-mouse

Overview

Clone MB9-3G8 specifically recognizes the mouse prominin-1 antigen, a glycoprotein with close structural similarity to its human ortholog, CD133. Prominin-1 is expressed on neural stem cells, for example, in the white matter of the cerebellum, on neuroepithelial tissue cells, and on various other epithelial cells in the mouse embryo. 5–10% of the neural cells found in the subventricular zone of postnatal mice have been shown to be prominin-1-positive. In the adult mouse, prominin-1 has been detected in the brain ependymal layer and in kidney tubules.

Alternative names

PROM1, AC133, CD133

Detailed product information

Technical specifications

CloneMB9-3G8
Clonalitymonoclonal
Isotyperat IgG1
Isotype controlIsotype Control Antibody, rat IgG1
Hostrat
Type of antibodyPrimary antibodies
Speciesmouse
AntigenProminin-1
Alternative names of antigenPROM1, AC133, CD133
Molecular mass of antigen [kDa]95
Entrez Gene ID19126
RRIDAB_2660073, AB_2660074, AB_615141, AB_2784446

Resources for Prominin-1 Antibody, anti-mouse

References for Prominin-1 Antibody, anti-mouse

Publications

  1. Weigmann, A. et al. (1997) Prominin, a novel microvilli-specific polytopic membrane proteine of the apical surface of epithelial cells, is targeted to plasmalemmal protrusions of non-epithelial cells. Proc. Natl. Acad. Sci. U.S.A. 94: 12425-12430
  2. Singh, S.K. et al. (2003) Identification of a cancer stem cell in human brain tumors. Cancer Res. 63: 5821-5828
  3. Lee, A. et al. (2005) Isolation of neural stem cells from the postnatal cerebellum. Nat. Neurosci. 8: 723-729
  4. Corbeil, D. et al. (2001) Prominin: a story of cholesterol, plasma membrane protrusions and human pathology. Traffic 2: 82-91

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