MACS
®
GMP T Cell TransAct™ is intended for the
in vitro
stimulation and expansion of human T cells from hematological cell populations (e.g. PBMCs or enriched T cells).

Specifications for
MACS
®
GMP T Cell TransAct™

Overview

MACS
®
GMP T Cell TransAct™ is intended for the
in vitro
stimulation and expansion of human T cells from hematological cell populations (e.g. PBMCs or enriched T cells).

Detailed product information

Background information

Polyclonal T cell expansion can be used in applications of cellular therapy when increased numbers of effector cells are required or when T cells are activated to improve gene modification.
MACS
®
GMP T Cell TransAct™ consists of a colloidal polymeric nanomatrix covalently attached to humanized recombinant agonists against human CD3 and CD28.
Due to the nanomatrix MACS GMP T Cell TransAct can be sterile filtered and excess reagent can be removed by centrifugation and following conventional supernatant replacement or simply by medium wash. This reagent is suitable for the use in automated culture systems, such as the CliniMACS Prodigy
®
Instrument.
MACS GMP T Cell TransAct:
The reagent is optimized to activate and expand 1×10
8
enriched T cells.
MACS GMP T Cell TransAct - Large Scale:
The reagent is optimized to activate and expand up to 4×10
8
enriched T cells.

Applications

MACS
®
GMP T Cell TransAct
TM
is intended for the
in vitro
stimulation and expansion of human T cells from hematological cell populations (e.g. PBMC or enriched T cells).

Quality statement

MACS GMP Products are manufactured and tested under a quality management system (ISO 13485) and are in compliance with relevant GMP guidelines. They are designed following the recommendations of USP <1043> on ancillary materials.

Disclaimer

MACS GMP Products are for research use and
ex vivo
cell culture processing only, and are not intended for human
in vivo
applications. For regulatory status in the USA, please contact your local representative.

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®
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