Anti-HLA-DR MicroBeads have been developed for positive selection or depletion of antigen-presenting cells from PBMCs, cord blood, bone marrow, and tissue.

Data and images for Anti-HLA-DR MicroBeads

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Figure 1

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Separation of human PBMCs using Anti-HLA-DR MicroBeads and MiniMACS™ Separator with an MS Column. Cells are stained with Anti-HLA-DR-FITC.

Figure 1

Separation of human PBMCs using Anti-HLA-DR MicroBeads and MiniMACS™ Separator with an MS Column. Cells are stained with Anti-HLA-DR-FITC.

Specifications for Anti-HLA-DR MicroBeads

Overview

Anti-HLA-DR MicroBeads have been developed for positive selection or depletion of antigen-presenting cells from PBMCs, cord blood, bone marrow, and tissue.

Detailed product information

Background information

The HLA-DR antigen is constitutively expressed on professional antigen-presenting cells (dendritic cells, B cells, monocytes/macrophages), and its expression is further up-regulated upon activation. On T cells, NK cells, hematopoietic precursor cells, and some epithelial cells the expression of HLA-DR is induced by cell activation.

Downstream applications

HLA-DR–positive cells are isolated, for example, for serological typing of HLA class II molecules or studies on antigen presentation.

Columns

For positive selection: MS, LS, XS, or autoMACS
®
Columns. For depletion: LD, D, or autoMACS Columns.

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